About Bridge2AI
Bridge2AI aims to propel biomedical research into a new era of ethical data-driven discovery. We empower researchers, clinicians, and communities to collaboratively generate high-quality, ethically sourced datasets that reflect the diversity of the human experience.
Our Vision: A future where artificial intelligence (AI) in biomedicine is powered by data that is representative, trustworthy, and ready for use in advancing health outcomes equitably across all populations.
Grand Challenges
Bridge2AI’s Grand Challenges are ambitious, collaborative efforts to generate high-quality biomedical and behavioral datasets ready for ethical, inclusive, and impactful AI development.
Each Grand Challenge focuses on creating AI-ready data that is FAIR—Findable, Accessible, Interoperable, and Reusable—and that upholds the highest standards for diversity, equity, and ethics. Together, these efforts are laying the groundwork for AI tools that can tackle some of the most complex questions in human health, from lifelong wellness to personalized clinical decision-making.
In addition to generating new datasets, each Grand Challenge develops tools, training materials, and best practices that support multidisciplinary collaboration and ethical data generation across the scientific community.
AI/ML for Clinical Care
Creating ethically sourced clinical datasets to advance the development of trustworthy AI tools that support real-world decision-making at the bedside
Functional Genomics
Generating rich, annotated datasets that help decode how genes and molecular pathways influence disease risk and treatment response
Precision Public Health
Harnessing AI to understand how social, environmental, and structural factors influence health outcomes across diverse populations
Salutogenesis
Exploring the drivers of health and well-being through longitudinal, person-centered data designed to capture the full spectrum of human experience
Bridge Center
The Bridge Center serves as the coordinating hub for all Bridge2AI activities. We support Data Generation Projects and the broader AI research community by:
- Providing training and resources to build team science and responsible AI skills
- Offering centralized tools and shared infrastructure
- Facilitating cross-project collaboration and learning
- Ensuring harmonization across datasets, practices, and goals
Together, we’re building a foundation for biomedical AI that is robust, equitable, and ready to scale.
Working Groups
Communications, Meetings, & Portal
Coordinating communications, meetings, and resources to keep the Bridge2AI community connected, collaborative, and accessible to all
Data Sharing & Dissemination
Promoting ethical and transparent sharing of biomedical data by developing best practices, consent processes, and tools to support responsible open science in AI
Dissemination & Open House
Showcasing Bridge2AI’s progress through public engagement & Open House events, fostering connections across internal teams and external stakeholders
Ethical, Legal, & Social Implications (ELSI)
Advancing ethical, legal, and social best practices to ensure AI in health research is trustworthy, equitable, and grounded in respect for individuals and communities
Teaming & Collaboration
Fostering inclusive, cross-disciplinary collaboration by building trust, shared vision, and best practices that empower effective team science across Bridge2AI
Training, Recruitment, & Mentoring
Equipping the next generation of diverse scientists with the skills, mentorship, and training needed to responsibly apply AI in biomedical and behavioral research
Standards, Practices, & Quality Assessment
Developing community-driven standards to ensure Bridge2AI data and tools are high-quality, reproducible, and broadly reusable across biomedical and behavioral research
Sub-Groups & Committees
Blockchain Task Force
Designing a decentralized, transparent system to track and accredit Bridge2AI digital assets, from datasets to models, through prototype development and evaluation with Data Generation Projects
External Advisory Board
Providing independent expert review of Bridge2AI activities to strengthen scientific rigor and impact, offering objective advice and evaluation to the Bridge Center and Grand Challenge teams
Join the Bridge2AI Community
Connect, collaborate, and contribute to our growing AI/ML biomedical research community. There are many ways to get involved—whether online or in-person.
Participate in Events
Take part in our public events—including datathons, challenges, seminars, paper submissions, and study participation opportunities—and help advance our work.
Acknowledgments
Bridge2AI is funded by the National Institutes of Health (NIH) Common Fund and is powered by the contributions of a nationwide network of researchers, institutions, and partners.
