Tools Optimization Core

The Tool Optimization Core (TOC) will serve as a national and multi-national hub for algorithmic and methodologic innovation, benchmarking, standardization, optimization, and dissemination. The Tool Optimization Core is envisioned as a Commons, servicing a broad and diverse range of stakeholders, including the B2AI Data Generation Projects (DGPs), data consumers, algorithm developers, algorithm users, citizen scientists, regulatory bodies and members of the public. Each stakeholder has their own battery of needs, which the TOC addresses by establishing a nexus of expertise, innovation, and dissemination that will support tool optimization across B2AI.

The TOC will be a hub for algorithm development, benchmarking, optimization, and dissemination across B2AI, delivering: advice to DGPs in tool development, benchmarking, and software engineering; open and coordinated tool development within and beyond B2AI, with area-specific working groups; regular B2AI-wide benchmarks of key tools, linked to gold standard data and educational materials (with SWD); a harmonized database of tools used across B2AI, linked to systematic meta-information (with Standards); tool search and help interfaces customized for stakeholder groups; consensus workshops and systematic training materials on B2AI-wide best analytical practices (with SWD); ongoing identification of gaps in tool development across B2AI; and focused algorithm-development efforts internally and through funding to fill tool and data gaps within the program. Through its efforts, the TOC will foster dissemination of best practices.

Who We Are

Paul Boutros, PhD, MBA
Core Lead
UC Los Angeles
Jake Albrecht, PhD
Co-Lead
Sage Bionetworks
Alex Bui, PhD
Co-Lead
UC Los Angeles
Kyle Ellrott, PhD
Co-Lead
OHSU
Peipei Ping, PhD
Co-Lead
UC Los Angeles
Wei Wang, PhD
Co-Investigator
UC Los Angeles