Cell Maps for AI (CM4AI) Grand Challenge
![Illustration for Cell Maps For AI DGP](https://bridge2ai.org/wp-content/uploads/2023/03/CM4AI-Approved-Graphic-3-1.png)
The Functional Genomics Grand Challenge seeks to map the spatiotemporal architecture of human cells and use these maps toward the grand challenge of interpretable genotype-phenotype learning. In genomics and precision medicine, machine learning models are often “black boxes,” predicting phenotypes from genotypes without understanding the mechanisms by which such translation occurs. To address this deficiency, this project will launch a coordinated effort involving three complementary mapping approaches – proteomic mass spectrometry, cellular imaging, and genetic perturbation via CRISPR/Cas9 – creating a library of large-scale maps of cellular structure/function across demographic and disease contexts.
Who We Are
![Headshot for Trey Ideker.](https://bridge2ai.org/wp-content/uploads/2023/03/ideker_headshot_cropped-231x300.jpg)
Contact Principal Investigator
University of California San Diego
![Headshot for J-C Bélisle-Pipon.](https://bridge2ai.org/wp-content/uploads/2023/03/Jean-ChristopheBélisle-Pipon2_web_cropped-231x300.jpg)
Principal Investigator
Simon Fraser University
![Headshot for Jake Chen.](https://bridge2ai.org/wp-content/uploads/2023/03/Jake-Chen_cropped-231x300.jpg)
Principal Investigator
University of Alabama at Birmingham
![Headshot for Timothy Clark.](https://bridge2ai.org/wp-content/uploads/2023/03/TimClark_cropped-231x300.png)
Principal Investigator
University of Virginia
![Headshot for Nevan Krogan.](https://bridge2ai.org/wp-content/uploads/2023/03/NevanKrogan_cropped-231x300.jpg)
Principal Investigator
University of California San Francisco
![Headshot for Emma Lundberg.](https://bridge2ai.org/wp-content/uploads/2023/03/emma_lundberg_cropped-231x300.jpg)
Principal Investigator
Stanford University
![Headshot for Prashant Mali.](https://bridge2ai.org/wp-content/uploads/2023/03/Prashant_2_cropped-231x300.jpg)
Principal Investigator
University of California San Diego
![Headshot for Vardit Ravitsky.](https://bridge2ai.org/wp-content/uploads/2023/03/Vardit_Ravitsky_cropped-231x300.jpg)
Principal Investigator
University of Montreal
![Headshot for Wade Shulz.](https://bridge2ai.org/wp-content/uploads/2023/03/wade_shulz_cropped-231x300.png)
Principal Investigator
Yale University
![Headshot for Cynthia Brandt.](https://bridge2ai.org/wp-content/uploads/2023/03/CynthiaBrandt_cropped-231x300.jpg)
Co-PI
Yale University
![Headshot for Ying DIng.](https://bridge2ai.org/wp-content/uploads/2023/03/YingDing_cropped-231x300.jpg)
Co-PI
University of Texas at Austin
![Headshot for Sarah Ratcliffe.](https://bridge2ai.org/wp-content/uploads/2023/03/Ratcliffe_photo_2017_cropped-231x300.jpg)
Co-PI
University of Virginia
![Headshot for Andrej Sali.](https://bridge2ai.org/wp-content/uploads/2023/03/AndrejSali_cropped-231x300.jpg)
Co-PI
University of California San Francisco